International Journal For Multidisciplinary Research

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Trends in HDL Level and LDL/HDL Ratio Among Patients Attending a Tertiary Care Hospital in Silchar: A Retrospective Analysis

Author(s) Dr. Adrita Syam Choudhury, Dr. Mousumi Das, Dr. Biswadeep Choudhury
Country India
Abstract Dyslipidemia, particularly low high-density lipoprotein (HDL) cholesterol and an elevated LDL/HDL ratio, is a major contributor to atherosclerotic cardiovascular disease and is highly prevalent in South Asian populations. This retrospective cross-sectional study evaluated trends in HDL levels, LDL levels, and LDL/HDL ratios among adult patients attending a tertiary care hospital in Silchar, Northeast India. Lipid profile data of 8,955 adults (≥18 years) collected between April 2024 and March 2025 were analyzed using laboratory information system records. The mean HDL and LDL levels were 37.03 mg/dL and 102.80 mg/dL, respectively, with a mean LDL/HDL ratio of 3.13, exceeding established atherogenic risk thresholds. Sub-optimal HDL levels were observed in 68% of males and 82% of females. LDL levels and LDL/HDL ratios demonstrated a progressive increase with advancing age. Despite higher mean HDL levels in women, a greater proportion exhibited sub-optimal HDL concentrations. These findings highlight a distinct dyslipidemic pattern characterized by low HDL and elevated LDL/HDL ratios, underscoring a substantial cardiovascular risk burden in the Northeast Indian population and emphasizing the need for region-specific preventive strategies.
Keywords Dyslipidemia, High-density lipoprotein (HDL), LDL/HDL ratio, Northeast India
Field Biology > Medical / Physiology
Published In Volume 7, Issue 6, November-December 2025
Published On 2025-12-31
DOI https://doi.org/10.36948/ijfmr.2025.v07i06.65193

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