LIPID PROFILE AND TARGET ORGAN DAMAGE IN ADULTS WITH HYPERTENSION: A RETROSPECTIVE CROSS-SECTIONAL STUDY

JAGADISH MANTHENA; UMESH BABU MG; VINOD BHARANI

doi:10.36948/ijfmr.2026.v08i01.65370

LIPID PROFILE AND TARGET ORGAN DAMAGE IN ADULTS WITH HYPERTENSION: A RETROSPECTIVE CROSS-SECTIONAL STUDY

Author(s)	Mr. JAGADISH MANTHENA, Dr. UMESH BABU MG, Dr. VINOD BHARANI
Country	India
Abstract	ABSTRACT BACKGROUND: Hypertension and dyslipidemia frequently coexist and synergistically increase cardiovascular risk through development of target organ damage (TOD). Comprehensive evaluation of lipid abnormalities in relation to multi-organ TOD in established hypertension is limited in Indian populations. AIM: To retrospectively evaluate the prevalence of dyslipidemia and target organ damage in hypertensive patients and examine associations between lipid parameters and organ damage markers using visual epidemiological analysis. METHODS: Hospital medical records from 240 hypertensive adults (May 2025- December 2025) were reviewed. Comprehensive investigations included lipid profile, electrocardiography, echocardiography, urinalysis, retinal examination, and pulse wave velocity. Associations were assessed using t-tests and correlations. Data visualization included pie charts (proportions), bar graphs (prevalence), and scatter plots (correlations). RESULTS: Mean age 54.4 ± 11.3 years (50.4% male); systolic BP 156.7 ± 13.4 mmHg. Dyslipidemia: 238/240 (99.2%). Target organ damage present in 213/240 (88.8%), including microalbuminuria (52.5%), hypertensive retinopathy (46.7%), elevated pulse wave velocity (36.7%), and electrocardiographic left ventricular hypertrophy (34.2%). Multi-organ involvement (≥2 systems) in 126/240 (52.5%). Total and non-HDL cholesterol showed weak associations with retinopathy (p<0.05). Most lipid parameters demonstrated minimal correlation with individual TOD markers. CONCLUSION: Near-universal dyslipidemia coexists with highly prevalent target organ damage in established hypertension. Blood pressure elevation remains the primary determinant of organ injury; dyslipidemia plays a modulatory role. Comprehensive organ evaluation and intensive lipid management should be standard in established hypertension.
Keywords	hypertension; dyslipidemia; target organ damage; cross-sectional study; cardiovascular risk; retrospective analysis
Field	Medical / Pharmacy
Published In	Volume 8, Issue 1, January-February 2026
Published On	2026-01-07
DOI	https://doi.org/10.36948/ijfmr.2026.v08i01.65370
Short DOI	https://doi.org/

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LIPID PROFILE AND TARGET ORGAN DAMAGE IN ADULTS WITH HYPERTENSION: A RETROSPECTIVE CROSS-SECTIONAL STUDY

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