Inflammatory Bowel Disease: Historical Perspective, Current Management Strategies & Future Therapeutic Horizons

Author(s)	Ms. LEENA RAVINDRA THAKARE, Ms. Diya Dinesh Late, Ms. Ayesha Javed Shaikh, Ms. Priyanka Arun Sawant
Country	India
Abstract	The two main types of inflammatory bowel disease (IBD), which are defined by persistent gastrointestinal inflammation, are Crohn's disease (CD) and ulcerative colitis (UC). In addition to discussing current management approaches, such as corticosteroids, immunosuppressants, biologics, and surgery intended to achieve mucosal repair and modify disease progression, this study offers a historical perspective on IBD. Problems like adverse effects and therapeutic non-response still exist despite improvements. Precision medicine, which uses genetics, transcriptomics, and gut microbiome studies to predict individual therapy responses, is the way of the future for IBD care. In the upcoming years, more individualized, efficient, and secure patient care may be possible because of new treatments, innovative drug delivery methods, and the incorporation of artificial intelligence and digital health tools.
Keywords	Inflammatory Bowel Disease, Crohn’s Disease, Ulcerative Colitis, Intestinal Microbiota, Immune Dysregulation, Biologic Therapy, Precision Medicine, Artificial Intelligence
Field	Medical / Pharmacy
Published In	Volume 8, Issue 1, January-February 2026
Published On	2026-02-22
DOI	https://doi.org/10.36948/ijfmr.2026.v08i01.66674

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