International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 8, Issue 2 (March-April 2026) Submit your research before last 3 days of April to publish your research paper in the issue of March-April.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 8 Issue 2
March-April 2026

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

Subclinical Vitamin B12 Deficiency Presenting with isolated Red Cell Distribution Width (RDW) elevation without anemia in 20 years old female: A Rare hematological presentation : Case Study

Author(s) Mrs. Phool Lodhi
Country India
Abstract Megaloblastic anemia and neurological symptoms are common signs of vitamin B12 deficiency. However, the lack of traditional clinical and hematological findings may cause the condition to go undiagnosed in its early or subclinical stage. Before anemia develops, subtle changes in red cell indices, especially red cell distribution width (RDW), may act as early markers of compromised erythropoiesis.
This case study details a 20-year-old female patient who had mild, nonspecific fatigue and a rare presentation of subclinical vitamin B12 deficiency. Except for a single elevation in RDW, routine hematological analysis showed normal hemoglobin concentration, mean corpuscular volume, and other red cell parameters. Mild anisocytosis was revealed by peripheral smear analysis. Iron tests and other biochemical parameters were within normal ranges, but additional testing revealed decreased serum vitamin B12 levels.
Early detection of vitamin B12 deficiency allowed for the timely start of supplementation, which stopped the development of neurological issues and overt anemia. The diagnostic value of isolated RDW elevation as an early hematological indicator of subclinical vitamin B12 deficiency is demonstrated by this case.
Keywords Keywords: Vitamin B12, Red Cell Distribution Width (RDW), Megaloblastic anemia, Anisocytosis, Erythropoiesis.
Field Medical / Pharmacy
Published In Volume 8, Issue 1, January-February 2026
Published On 2026-02-05
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 8 Isu 2Cover Page Vol 8 Isu 1Cover Page Vol 7 Isu 6

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9687-828-838 editor@ijfmr.com
Powered by Sky Research Publication and Journals