International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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Study on Clinical Data Related to High Serum Vitamin B12 Levels

Author(s) Mr. Veeresh Sutagatti, Dr. Vinod George Thykadavil
Country India
Abstract Serum vitamin B12 measurements are routinely done to rule out vitamin B12 deficiency. Surprisingly, the number of samples for vitamin b12 measurement display high serum vitamin B12 levels. The present study investigated to identify the types of diseases that are showing high serum vitamin B12 levels and to find out the significant association between kidney diseases and high serum vitamin B12 levels. Based on earlier literature, elevated vitamin B12 levels can be found in patients with a variety of diseases, including diseases of the liver, kidney, and immune system as well as several different malignancies. In clinical practice, biomarkers are used as tests for diagnosis, prognosis, screening, and monitoring diseases. In these context, measurement of serum Vitamin B12 is requested to diagnose (or rule out) cobalamin deficiency in patients with the symptoms of haematological, gastrointestinal, and neurological kind.
Keywords cbl; cobalamin. HoloTC; Holo transcobalamin. IF; Intrinsic factor. MMA; Methylmalonic acid. CPB; Competitive protein binding. KCN; Potassium cyanide. HPLC; High performance liquid chromatography. EDTA; Ethylenediamine tetra acetic acid. TCBs; Transcobalamin’s. HC-cbl; Haptocorrin- cobalamin complex. AST; Aspartate transaminase. ALT; Alanine transaminase. GGT; Gamma glutamyl transferase. ALP; Alkaline phosphatase. Tc-II; Transcobalamin- II.
Field Medical / Pharmacy
Published In Volume 8, Issue 1, January-February 2026
Published On 2026-02-18
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E-ISSN 2582-2160
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