International Journal For Multidisciplinary Research

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A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 8, Issue 2 (March-April 2026) Submit your research before last 3 days of April to publish your research paper in the issue of March-April.

Evaluation of Ventilator-Associated Pneumonia Surveillance and impact of VAP care bundle in Neonatal and Pediatric Intensive Care Unit of Punjab

Author(s) Dr. Kiranjot Kaur Randhawa, Dr. Loveena Oberoi, Dr. Manmeet Kaur Sodhi, Dr. Sapna Batra
Country India
Abstract Introduction:- Ventilator-associated pneumonia (VAP) remains a significant cause of morbidity and mortality among critically ill neonates and children. Early diagnosis,microbiological surveillance, and implementation of care bundles are proven strategies to prevent VAP.
Objective: To conduct prospective surveillance of VAP, study microbial profiles with antibiotic resistance patterns, and evaluate the impact of VAP care bundle implementation in NICU and PICU patients.

Materials and Methods: A prospective interventional study was carried out at Government Medical College, Amritsar from January 2024 to February 2025 in three phases: pre-implementation, staff sensitization, and post-implementation. During the surveillance, the particulars of the patients including sociodemographic data, along with evolution of symptoms during hospitalization were recorded on a pre-designed proforma. The written informed consent was taken from all the patient’s guardians participating in the study. Endotracheal aspirates were collected, processed, and antimicrobial susceptibility testing was done as per CLSI guidelines.

Statistical Analysis: For statistically significance, p value of less than 0.05 was considered statistically significant.
• Chi square Test (x2)= (O-E)2/E where O = observed and E = Expected
• P value (probability value)

Results: 160 ventilated patients were included. The VAP incidence rate decreased significantly from 48.46 to 37.6 per 1000 ventilator days after bundle implementation (p=0.0025). A significant decrease in Device Utilization Ratio was observed from 0.37 to 0.24. Gram-negative bacilli predominated, with Klebsiella spp., Acinetobacter spp., and Pseudomonas spp. as major isolates.

Conclusion: The structured implementation of a VAP prevention bundle significantly reduced the incidence rate. Continued training, surveillance, and antibiotic stewardship are essential to sustain outcomes.
Keywords Ventilator-associated pneumonia, NICU, PICU, Care bundle, Antibiotic resistance, Surveillance
Field Biology > Medical / Physiology
Published In Volume 8, Issue 1, January-February 2026
Published On 2026-02-06

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