Evaluation of Antimicrobial Efficacy of ZnO Nanoparticles Against Staphylococcus Aureus and Escherichia Coli.

Author(s)	Dr. Ajay Kumar, Dr. Vikash vikash, Mr. Deepak Kumar
Country	India
Abstract	Zinc oxide nanoparticles (ZnO NPs) are widely used antimicrobials whose exact mechanism of action is still being explored. This study investigates the concentration-dependent efficacy of pre-synthesized ZnO NPs of varying sizes against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus. The nanoparticles were characterized using standard techniques including X-ray Diffraction, FT-IR Spectroscopy, Thermo-Gravimetric Analysis, and Transmission Electron Microscopy. All bacterial strains were cultured in Mueller Hinton (MH) broth. The minimum inhibitory concentration (MIC) for each set of nanoparticles was determined against the bacterial strains using the standard micro-dilution method. The results confirmed that ZnO NPs exhibit antimicrobial activity against the food borne pathogens S. aureus and E. coli
Keywords	ZnO nanoparticles, Antimicrobial activity, Staphylococcus Aureus, Escherichia Coli
Field	Chemistry
Published In	Volume 8, Issue 1, January-February 2026
Published On	2026-02-13

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