Management of Extensive Recalcitrant Dermatophytosis Using a Topical Propylene Glycol–Salicylic Acid Formulation: A Case Study

Author(s)	Dr. Naved Ahmed
Country	India
Abstract	Although dermatophytosis is a frequent superficial fungal infection, its severe, long-lasting, and resistant variants provide serious therapeutic hurdles. Poor drug penetration, topical agent abuse, and impaired skin barrier function have all been connected to an increase in reports of resistant dermatophytosis. In this case study, a 30-year-old male patient with widespread resistant dermatophytosis was successfully treated with a topical formulation that included high-concentration salicylic acid and propylene glycol. After traditional topical and systemic antifungal treatments failed, the patient saw quick symptom improvement within a week and full clinical remission within two months. The significance of keratolytic and penetration-enhancing techniques in the treatment of refractory dermatophytosis is demonstrated by this example.
Keywords	Dermatophytosis, Recalcitrant fungal infection, Salicylic acid, Propylene glycol, Keratolytic therapy.
Field	Medical / Pharmacy
Published In	Volume 8, Issue 3, May-June 2026
Published On	2026-05-20

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