International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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MORINGA OLEIFERA Pharmacological Uses: Recent Advancements and Translational Research

Author(s) Mr. Ratikesh Ashokrao Wawarkar, Mr. Swapnil Ramchandra Dudhakohar, Ms. Shraddha Raju Wasnik, Mr. Swayam Pramodrao Shingane
Country India
Abstract Abstract
Background: Moringa oleifera Lam., widely known as the "Miracle Tree" or "Drumstick Tree," is a perennial plant of the Moringaceae family recognized for its dual role in "medicine–food homology." Indigenous to the sub-Himalayan regions of Asia and widely naturalized in Africa, it is celebrated for its rapid growth, drought resistance, and extraordinary nutritional density.
Objective: This paper reviews the pharmacological potential, phytochemical composition, and recent translational research surrounding M. oleifera, focusing on its transition from traditional medicine to modern therapeutic applications.
Methods: The study synthesizes current knowledge on the nutritional and chemical profiles of various plant parts (leaves, seeds, roots, bark, and flowers) and examines their efficacy against chronic diseases through recent preclinical and clinical findings.
Results: Moringa oleifera is a potent source of proteins, essential amino acids, vitamins (A, C, E), and minerals (Calcium, Iron, Potassium). Phytochemical analysis reveals a rich concentration of flavonoids, polyphenols, and isothiocyanates, which contribute to its significant antioxidant, anti-inflammatory, and antimicrobial properties. Recent advancements highlight its potential in:
Oncology: Utilizing nano-encapsulation (PLGA-CS-PEG nanoparticles) to enhance the delivery of leaf extracts against colorectal, liver, and breast cancers.
Metabolic Disorders: Managing blood glucose levels in diabetes and reducing systolic/diastolic pressure in hypertension.
Dermatology & Virology: Promoting collagen synthesis and skin healing, while demonstrating inhibitory effects against respiratory viruses like HCoV-229E and Measles.
Conclusion: Moringa oleifera stands as a versatile, sustainable resource with the potential to combat global malnutrition and serve as a scaffold for novel pharmaceutical developments. While its safety profile is generally favourable, further clinical research is required to standardize dosages and evaluate long-term safety in specific populations, such as pregnant women and individuals with autoimmune conditions.
Keywords Moringa oleifera, Phytochemicals, Translational Research, Nanotechnology, Antihypertensive, Nutritional Security.
Field Medical / Pharmacy
Published In Volume 8, Issue 1, January-February 2026
Published On 2026-02-17
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E-ISSN 2582-2160
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