Restoration of Menstrual Cycles in High-Androgen PCOS Through Meal Timing Intervention and Inositol Supplementation: A Case Report

Author(s)	Dr Kavitha P S, Dr Ramana V Krishnan
Country	India
Abstract	This case report describes metabolic and reproductive recovery in a 23-year-old woman with high-androgen phenotype Polycystic Ovary Syndrome (PCOS), whose menstrual cycles had never been regular since menarche. Menstrual bleeding historically occurred primarily following hormonal birth control or withdrawal therapy and was frequently followed by prolonged amenorrhoea or episodes of excessive and painful bleeding. The patient also demonstrated significant insulin resistance. A structured intervention combining reduced meal frequency (initially two meals daily progressing to one meal per day), addition of inositol supplementation, and gradual weight reduction resulted in improved insulin sensitivity and restoration of spontaneous menstrual cycles. Menstrual quality improved from heavy and debilitating bleeding to normal-duration cycles permitting routine functioning. This case highlights the metabolic–reproductive relationship in PCOS and illustrates potential benefits of meal timing interventions combined with metabolic support.
Keywords	PCos, fasting, inositol
Field	Biology
Published In	Volume 8, Issue 1, January-February 2026
Published On	2026-02-20

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