Solid Lipid Nanoparticles (SLNs): A Comprehensive Review on Preparation, Characterization, and Drug Delivery Applications

Author(s)	Ms. Ayati Kar, Ms. Mayuri Upagya Kalita, Mr. Sandip Mandal
Country	India
Abstract	Solid Lipid Nano particles (SLNs)have become a viable drug delivery technology because of their special qualities, which include controlled drug release, biocompatibility, and biodegradability. There are numerous advantages to using these colloidal carriers in comparison to traditional delivery of drug techniques, including enhanced drug bioavailability, more precise distribution, and fewer adverse effects. Through the selection of suitable lipids and surfactants, SLNs (Solid Lipid Nano particles) can be customized to meet drug delivery requirements. Micro emulsion techniques, solvent emulsification evaporation, hot homogenization, and cold homogenization are some of the methods used to manufacture SLNs (Solid Lipid Nano particles). An extensive summary of SLNs (Solid Lipid Nano particles) is given in this review, covering their makeup, methods of preparation, characterization, and uses. Future directions for SLN technology research are also covered, emphasizing how these nanocarriers have the potential to completely transform administration of medication.
Keywords	Solid Lipid Nano particles, Drug delivery system, Nanocarrier technology, Targeted drug delivery, Biocompatibility.
Field	Chemistry > Pharmacy
Published In	Volume 8, Issue 2, March-April 2026
Published On	2026-03-16
DOI	https://doi.org/10.36948/ijfmr.2026.v08i02.71430

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