International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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Role of Mean Platelet Volume in differentiating the causes of Thrombocytopenia

Author(s) Dr. Navdeep Kaur, Dr. Monika Gupta, Dr. Megha Bansal, Dr. Nikhilesh Kumar, Dr. Ankita Srivastava, Dr. Honey Bhasker Sharma, Dr. Ritu Sharma, Dr. Aviral Srivastava, Dr. Ekta Jaiswal
Country India
Abstract BACKGROUND- Accurate evaluation of thrombocytopenic patients requires determination of the underlying etiology, specifically whether thrombocytopenia results from decreased platelet production or increased peripheral destruction, as this distinction has important implications for clinical management. The present study aims to assess the variations in Mean Platelet Volume and to analyze its relationship in patients with hypo-productive and hyper-destructive thrombocytopenia.
MATERIAL AND METHOD- 18 month cross-sectional study of 200 samples from thrombocytopenia patients. Mean Platelet Volume was recorded for all samples. Data were systematically entered into suitable software for analysis.
RESULT- Our study shows a male predominance with a mean age of 38.76 ± 14.1 years. The mean MPV was significantly higher in the hyper-destructive group (15.29 fl) compared to the hypo-productive group (9.49 fl). The difference in Mean Platelet Volume between the two groups was statistically significant.
CONCLUSION- Our study suggests that Mean Platelet Volume play a role in discerning the underlying cause of thrombocytopenia.
Keywords Thrombocytopenia; Platelet indices; Mean Platelet Volume; Hypoproductive; Hyperdestructive
Field Medical / Pharmacy
Published In Volume 8, Issue 2, March-April 2026
Published On 2026-03-16
DOI https://doi.org/10.36948/ijfmr.2026.v08i02.71679
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