Immune Stability and Metabolic Improvements During One-Meal-a-Day Time-Restricted Eating in a Patient With Long-Standing Human Immunodeficiency Virus Infection: A Case Report

Author(s)	Dr Kavitha P S, Dr Ramana V Krishnan
Country	India
Abstract	Time-restricted eating (TRE) has gained increasing attention for its potential metabolic benefits. Evidence describing TRE in individuals living with Human Immunodeficiency Virus Infection (HIV) remains limited. We report the case of a 51-year-old female with long-standing HIV infection who adopted a one-meal-per-day time-restricted eating regimen beginning in June 2025. Clinical records from 2011 through February 2026 were reviewed. Following the fasting intervention, the patient experienced: • 10 kg weight reduction • improvements in lipid profile and glycemic markers • resolution of gastrointestinal symptoms including bloating, acidity, nausea, and burping • improvement in cervical discomfort and headaches Immune parameters remained strong with CD4 counts near 1000 cells/µL and sustained viral suppression (<40 copies/mL).
Keywords	HIV , immunity, fasting
Field	Biology
Published In	Volume 8, Issue 2, March-April 2026
Published On	2026-03-16

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