Decoding Amla and Śiśira Prīti in Raktakṣaya: An Integrative Ayurvedic and Scientific Perspective

Author(s)	Dr. Ajitha Kumari Amma, Dr. Sreejith V
Country	India
Abstract	Raktakṣaya, described in Ayurveda as depletion of Rakta Dhatu, is characterized by distinctive features such as Amla Prīti (inclination toward sour taste) and Śiśira Prīti (preference for cold). These manifestations indicate underlying systemic adaptations rather than isolated symptoms. The present study interprets these classical observations using contemporary biomedical concepts. Alterations in gustatory receptor function, neurotransmitter dynamics, and cytokine-mediated regulatory mechanisms are proposed to explain Amla Prīti. Śiśira Prīti is understood through disturbances in thermoregulation, impaired mitochondrial energy metabolism, and vascular adaptations associated with anemic states. This integrative approach demonstrates that traditional Ayurvedic descriptions correspond to measurable physiological and molecular processes.
Keywords	Raktakṣaya, Amla Prīti, Śiśira Prīti, Iron Deficiency, Cytokines, Thermoregulation
Field	Medical / Pharmacy
Published In	Volume 8, Issue 2, March-April 2026
Published On	2026-03-21

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