International Journal For Multidisciplinary Research

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Phytochemical Screening and GC-MS Profiling of the Methanolic Fraction of Cryptocarya wightiana Thw

Author(s) Ms. MONISHA C PATIL, Dr. GOVINDAPPA M
Country India
Abstract Since ancient times, plants with medicinal value have been linked to traditional medicine, with plant-derived compounds providing various therapeutic potential. This study investigated the phytochemical composition of Cryptocarya wightiana Thw., a species belonging to the Lauraceae family, widely distributed in the Central Western Ghats of Karnataka, India. Fresh leaves were collected from Agumbe, Karnataka, and subjected to Soxhlet extraction using both polar and nonpolar solvents, based on their polarity. Among the tested solvents, the methanol extract had the greatest yield (29.2%) and was rich in secondary metabolites such as flavonoids, alkaloids, tannins, phenols, and saponins. Phytochemical screening confirmed that polar solvents extracted a broader range of bioactive compounds than nonpolar solvents did. Further analysis of the methanolic extract via gas chromatography-mass spectrometry (GC-MS) revealed 45 phytocompounds. The major constituents identified were cis-9-hexadecenal (45.51%), n-hexadecanoic acid (16.41%), octadecanoic acid (6.23%), 9-octadecenoic acid (Z)-, oxiranylmethyl ester (4.30%), and linoleyl acetate (2.88%), reported biological activities such as antioxidant, antimicrobial, and anti-inflammatory effects. These findings provide a baseline chemical profile of C. wightiana, supporting its traditional use in herbal medicine and facilitating future pharmacological validation and comparative studies with other solvent extracts.
Keywords Medicinal plants, Cryptocarya wightiana Thw, Lauraceae, Methanol extract, Phytochemicals, Gas chromatography–mass spectrometry
Field Biology
Published In Volume 8, Issue 2, March-April 2026
Published On 2026-03-26
DOI https://doi.org/10.36948/ijfmr.2026.v08i02.72515
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