International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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Chylous Ascites as a Presentation of Early T-Precursor Acute Lymphoblastic Leukaemia: A Case Report

Author(s) Dr. Eu Ming Yong, Dr. Rachel Yi Ying Wong, Dr Jiun Yan Tan, Dr Amy Amutha Amanda Muthu Krishnan, Dr Mohd Nadzri Misni
Country Malaysia
Abstract Chylous ascites is an uncommon cause of abdominal distension resulting from the accumulation of triglyceride-rich lymphatic fluid within the peritoneal cavity. Malignancy, particularly lymphoma, is a major non-traumatic etiology; however, the presentation of lymphoblastic neoplasms with chylous ascites as an initial feature is rare and may delay diagnosis. We describe an 18-year-old previously healthy woman who presented with progressive abdominal distension and generalized lymphadenopathy. Paracentesis demonstrated milky ascitic fluid with elevated triglyceride levels, confirming chylous ascites. Cross-sectional imaging revealed extensive lymphadenopathy with hepatosplenomegaly, raising suspicion for a lymphoproliferative disorder. Excisional lymph node biopsy established T-lymphoblastic lymphoma with a high proliferative index. During follow-up, the patient developed pancytopenia with circulating blasts, and bone marrow examination demonstrated infiltration with immunophenotypic features consistent with early T-precursor acute lymphoblastic leukemia (ETP-ALL). This case highlights chylous ascites as an unusual initial manifestation of T-lymphoblastic lymphoma and emphasizes the continuum between lymphoblastic lymphoma and acute lymphoblastic leukemia.
Field Medical / Pharmacy
Published In Volume 8, Issue 2, March-April 2026
Published On 2026-03-30
DOI https://doi.org/10.36948/ijfmr.2026.v08i02.73050
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E-ISSN 2582-2160
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