International Journal For Multidisciplinary Research
E-ISSN: 2582-2160
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A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal
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Volume 8 Issue 2
March-April 2026
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The Biology and Philosophy of stress : An integrative review of contemporary perspectives through unani conceptualization
| Author(s) | Dr. Syed Sumiya Ara Parveen, Dr. S.A.Khadir Hussaini, Dr.M.A.Lateef Siddiqui, Dr.Amreen, Dr. Meenaz Fathima |
|---|---|
| Country | India |
| Abstract | Stress has become a pervasive aspect of daily life, particularly in the post-COVID-19 era. A 2024 online survey of 1,479 adults in India reported that approximately 85% of individuals experienced moderate stress, while 10% had mild stress and 5% severe stress. Historically, stress research began in the early 19th century with Cannon’s description of physiological responses to nociceptive stimuli and the concept of homeostasis. Selye later defined stress as the non-specific response of the body to any demand. In Unani medicine, stress is understood as an imbalance of humors (Akhlat), particularly Safra and Sauda, resulting from internal and external factors. Pathophysiologically, stress activates the hypothalamic–pituitary–adrenal (HPA) axis and sympathetic-adreno-medullary system, increasing cortisol and catecholamines, which impact metabolism, immunity, and psychological state. Unani concepts emphasize the influence of environmental factors (Hawa), diet (Makool wa Mashroob), bodily and mental activity (Harkat wa Sukoon), sleep patterns (Naum wa Yaqza), and retention/evacuation (Ihtebaas wa Istifragh) on Mizaj (temperament). Excessive stress disrupts physiological and mental equilibrium, manifesting as anxiety, insomnia, fatigue, and cognitive disturbances. Integrating modern and Unani perspectives highlights the importance of lifestyle, diet, sleep, and environmental management for stress prevention and health maintenance. |
| Keywords | Stress, Unani medicine, Humoral imbalance, Mizaj, Safra, Sauda, HPA axis, Cortisol, Anxiety, Insomnia, Sleep, Diet, Environmental factors, Neuroendocrine response, Post-COVID stress, Psychological and physical stressors |
| Field | Medical / Pharmacy |
| Published In | Volume 8, Issue 2, March-April 2026 |
| Published On | 2026-04-08 |
| DOI | https://doi.org/10.36948/ijfmr.2026.v08i02.73775 |
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E-ISSN 2582-2160
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IJFMR DOI prefix is
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