Formulation and Evaluation of Gymnema Based Lozenges for Sweet Taste Suppression and Oral Health

Sanjey K; Riya K S; Nandhana Sudheer; Thulasi Sivaraman; Srikavi Anbalagan

doi:10.36948/ijfmr.2026.v08i02.74019

Formulation and Evaluation of Gymnema Based Lozenges for Sweet Taste Suppression and Oral Health

Author(s)	Mr. Sanjey K, Ms. Riya K S, Ms. Nandhana Sudheer, Dr. Thulasi Sivaraman, Dr. Srikavi Anbalagan
Country	India
Abstract	This study reports on the formulation and preliminary evaluation of a novel sugar-free herbal oral lozenge developed from a combination of natural and functional ingredients. The lozenge was prepared using an Isomalt base, a sugar substitute well-suited for oral dosage forms due to its low cariogenicity and favorable physical properties. The active herbal components incorporated into the formulation include Gymnema sylvestre, Tulsi (Ocimum sanctum), and Sukku (dry ginger), each selected for their well-documented therapeutic and antimicrobial properties.A key functional feature of this formulation is the inclusion of gymnemic acid, the bioactive constituent of Gymnema sylvestre, which reversibly binds to sweet taste receptor sites on the tongue, thereby producing a temporary inhibition of sweet taste perception. This unique mechanism positions the lozenge as a potential aid in managing sugar cravings and supporting dietary interventions. Inulin, a soluble prebiotic fiber, was also incorporated to promote the growth of beneficial oral and gut microbiota, adding a further dimension to the lozenge’s health-promoting profile.Preliminary evaluations included phytochemical screening to identify and characterize the principal bioactive plant-derived constituents responsible for the observed therapeutic effects. Antimicrobial activity was assessed using standard microbiological techniques against selected bacterial and fungal strains relevant to oral health. The combined results aim to validate the multifunctional potential of this lozenge, encompassing antimicrobial efficacy, sweet taste modulation, and prebiotic activity. This formulation represents a promising step toward developing evidence-based, natural oral care products with broad therapeutic applications.
Keywords	Herbal oral lozenge; Gymnema sylvestre; Sweet taste inhibition; Isomalt; Inulin; Prebiotic; Antimicrobial activity; Phytochemical analysis; Natural oral care; Sugar-free formulation
Published In	Volume 8, Issue 2, March-April 2026
Published On	2026-04-09
DOI	https://doi.org/10.36948/ijfmr.2026.v08i02.74019

View / Download PDF File

E-ISSN 2582-2160

doi

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads

Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 8 Isu 2 Cover Page Vol 8 Isu 1 Cover Page Vol 7 Isu 6

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA

About IJFMR Fees & Payment Current Issue Publication Archive	Submit Research Paper Track Submission Status Publication Guidelines Publication Ethics Peer Review & Plagiarism	Join as a Reviewer Editors & Reviewers Reviewer Referral Program Get Reviewer Membership Certi.	Website/Journal Policies Usage Policy Content Policies Privacy Policy

Contact Us		+91-9687-828-838	editor@ijfmr.com

International Journal For Multidisciplinary Research

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Formulation and Evaluation of Gymnema Based Lozenges for Sweet Taste Suppression and Oral Health

Share this