A Study on the Comparison of Dexmedetomidine as an Adjuvant to Intrathecal Bupivacaine Versus Bupivacaine Alone in Lower Abdominal & Lower Limb Surgeries

Author(s)	Mr. Syed Imran Hussain, Dr. Abhishek Gupta, Mr. Ishfaq Ramzan, Dr. Hilal Ahmed
Country	India
Abstract	Background Spinal anaesthesia is a widely practised regional anaesthetic technique for lower abdominal and lower limb surgeries. The use of intrathecal adjuvants has been explored to enhance the quality and duration of spinal anaesthesia. Dexmedetomidine, a highly selective alpha-2 adrenergic agonist, has gained attention as an effective intrathecal adjuvant because of its analgesic, sedative, and sympatholytic properties Methods: A total of 60 patients aged between 20–60 years, belonging to ASA physical status I and II, undergoing lower limb surgeries and caesarean section under spinal anaesthesia were included in the study. The patients were randomly divided into two groups. Group A (n=30): Received 3 ml of 0.5% hyperbaric bupivacaine intrathecally. Group B (n=30): Received 3 ml of 0.5% hyperbaric bupivacaine with 5 μg dexmedetomidine intrathecally. Results: The addition of dexmedetomidine to intrathecal bupivacaine resulted in faster onset of sensory block. Hemodynamic parameters remained stable in both groups, and adverse effects were minimal and manageable. Conclusion: Dexmedetomidine prolongs the duration of spinal anaesthesia and provides better postoperative analgesia without significant side effects.
Keywords	KEYWORDS: Spinal anaesthesia, Bupivacaine, Dexmedetomidine.
Field	Medical / Pharmacy
Published In	Volume 8, Issue 2, March-April 2026
Published On	2026-04-09

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