International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 8, Issue 2 (March-April 2026) Submit your research before last 3 days of April to publish your research paper in the issue of March-April.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 8 Issue 2
March-April 2026

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

Synthesis, Characterization and Antimicrobial Evaluation of New Di-schiff Bases Derived from 2,2′ - [butane-1,4-diylbis(oxy)] dibenzaldehyde

Author(s) Mr. Mayur Ramesh Badhe, Dr. Tushar S. Umasare
Country India
Abstract Two novel di-Schiff bases were synthesized through the condensation of the prepared dialdehyde intermediate, 2,2′-[butane-1,4-diylbis(oxy)]dibenzaldehyde, with amine moieties, namely semithiocarbazide and 4-aminoantipyrine, in a 2:1 molar ratio using DMF as the reaction medium under controlled conditions. The progress of the reactions and the purity of the synthesized compounds were monitored by thin-layer chromatography (TLC). The obtained Schiff bases were characterized by solubility tests, melting point determination, FT-IR spectroscopy, and elemental analysis. The compounds were found to be partially soluble in most organic solvents while remaining insoluble in water. The antimicrobial potential of the synthesized Schiff bases was evaluated by the disc diffusion method on agar medium against selected Gram-positive and Gram-negative bacterial strains, Bacillus subtilis, Staphylococcus aureus, Proteus vulgaris, and Escherichia coli, along with the fungal strain Candida albicans, at three different concentrations. The results revealed that the Schiff bases exhibited variable inhibitory activity against the tested microorganisms, indicating their promising antimicrobial properties.
Keywords Semithiocarbazide, 4-amino antipyrine, Schiff bases, Antimicrobial Activities
Field Chemistry
Published In Volume 8, Issue 2, March-April 2026
Published On 2026-04-10
DOI https://doi.org/10.36948/ijfmr.2026.v08i02.74196
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 8 Isu 2Cover Page Vol 8 Isu 1Cover Page Vol 7 Isu 6

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9687-828-838 editor@ijfmr.com
Powered by Sky Research Publication and Journals