International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

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Volume 8 Issue 2
March-April 2026

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Minimum Inhibitory Concentration Analysis of Senna alexandrina (Cassia angustifolia) Extracts Against Selected Pathogenic Microorganisms

Author(s) Dr. Khushbu Gautam
Country India
Abstract The increasing prevalence of antimicrobial resistance has stimulated interest in plant-derived antimicrobial agents. Senna species (Cassia angustifolia and related taxa) are widely used medicinal plants known for their laxative and pharmacological properties, yet their antimicrobial potential requires further investigation. The present study evaluates the minimum inhibitory concentration (MIC) of Senna leaf extracts against selected bacterial and fungal pathogens. Plant extracts were prepared using solvents such as methanol, ethanol, and aqueous media and tested against organisms including Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans using broth microdilution assays. Results demonstrated that Senna extracts exhibited measurable inhibitory effects with MIC values ranging between 4–128 µg/mL depending on the solvent system and microbial strain. Methanolic extracts showed the strongest antimicrobial activity compared to aqueous extracts. The findings suggest that bioactive phytochemicals present in Senna, such as flavonoids, anthraquinones, and sennosides, may contribute to antimicrobial activity. These results highlight the potential of Senna extracts as natural antimicrobial agents and warrant further investigation for pharmaceutical applications
Keywords Keywords: Senna extract, Cassia angustifolia, minimum inhibitory concentration, antimicrobial activity, medicinal plants, phytochemicals
Field Biology > Bio + Chemistry
Published In Volume 8, Issue 2, March-April 2026
Published On 2026-04-12
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E-ISSN 2582-2160
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