International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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Volume 8 Issue 2
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Formulation, Evaluation, and Antimicrobial Effect of Wound Healing Cream for Burns

Author(s) Ms. Shani S, Dr. Thangavel M, Ms. Aiswarya R, Mr. Dinesh S
Country India
Abstract The present research was carried out to formulate and evaluate a herbal burn wound-healing cream using aqueous extracts of Ricinus communis, Plectranthus amboinicus, and Mangifera indica, supplemented with animal fat as an emollient. These plant species were selected based on their well-documented pharmacological properties, including anti-inflammatory, antimicrobial, antioxidant, tissue-regenerative, and burn wound-healing activities. The cream was formulated using an oil phase consisting of coconut oil (1 ml), almond oil (0.6 ml), beeswax (0.5 g), emulsifying agent (1 g), castor oil (0.2 ml), and animal fat (0.2 ml), combined with an aqueous phase of distilled water (4.5 ml), glycerine (1.5 ml), and herbal plant extracts of Ricinus communis (0.17 ml), Plectranthus amboinicus (0.16 ml), and Mangifera indica (0.17 ml). The formulated cream demonstrated favourable physicochemical properties, including a pH of 7, spreadability of 4.3 cm, no irritation on human volunteers, and easy washability. The cream exhibited notable antibacterial activity with a zone of inhibition of 16 mm against Staphylococcus aureus. Phytochemical screening confirmed the presence of alkaloids, flavonoids, tannins, saponins, and terpenoids in the extracts. Microbial load testing showed less than 100 colonies per gram, confirming the microbiological safety of the preparation. The study highlights the potential of this animal-fat-enriched herbal formulation as a safe, natural, and effective burn wound-healing agent, providing scientific support for the traditional use of these medicinal plants in burn care management.
Keywords Ricinus communis, Plectranthus amboinicus, Mangifera indica, Burn Wound, Animal Fat, Herbal Cream.
Published In Volume 8, Issue 2, March-April 2026
Published On 2026-04-13
DOI https://doi.org/10.36948/ijfmr.2026.v08i02.74632
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