International Journal For Multidisciplinary Research

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Clinical Evaluation of Synthesis Repertory in the Management of Hypothyroidism with Individualised Homoeopathic Medicines: A Prospective Observational Study

Author(s) Dr. Susira Suresh, Dr. Kavya Kondoju, Dr. Vishal V. Deshpande
Country India
Abstract Background:
Hypothyroidism is a common endocrine disorder which is conventionally managed with lifelong Levothyroxine therapy. However, symptom relief is often incomplete. Homoeopathy, emphasizing individualized treatment through repertorial analysis, may offer complementary benefits.
Aim:
To assess the effectiveness of Individualized Homoeopathic Medicines selected using Synthesis Repertory in Hypothyroidism.
Materials and Methods:
A prospective observational study was conducted on 30 Hypothyroid adults (18–65 years) with hypothyroidism (ICD‑11: 5A00.Z), TSH 4.5–10 µIU/L, both sexes, on allopathic medicine. Inclusion requires uncontrolled thyroid values within this range and documented informed consent at JIMS Homoeopathic Medical College and Hospital. Remedies were selected through repertorial analysis using Synthesis Repertory. Patients were followed up for six months, with outcomes measured using Zulewski Clinical Score and Thyroid Function Tests (T3, T4, TSH). Statistical analysis was performed using the Friedmann’s ANOVA test.
Results:
Significant improvement was observed in clinical symptoms and Thyroid function parameters. Zulewski scores decreased in most patients and laboratory values showed positive changes. Statistical analysis confirmed improvement (p < 0.0001).
Conclusion:
Individualized Homoeopathic treatment based on repertorial analysis with the help of Synthesis Repertory demonstrated beneficial effects in Hypothyroidism, improving both clinical and biochemical outcomes. It may serve as a good complementary therapeutic option.
Keywords Hypothyroidism, Synthesis Repertory, Individualized Homoeopathic Medicine
Field Medical / Pharmacy
Published In Volume 8, Issue 2, March-April 2026
Published On 2026-04-16
DOI https://doi.org/10.36948/ijfmr.2026.v08i02.74799
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