International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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Volume 8 Issue 2
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Phytochemical Profiling and Preliminary In Vitro Anti-diabetic Evaluation of Millingtonia hortensis L. and Mimusops elengi L

Author(s) Mrs. Durga P Gupta, Dr. Sheelpriya Walde, Mrs. Prachi Rohit Moon, Mr. Amar Jaiswal
Country India
Abstract Diabetes mellitus is a chronic metabolic disorder marked by elevated blood glucose levels and long-term complications affecting multiple organ systems. Increasing interest in natural therapeutics has prompted the evaluation of medicinal plants as alternative antidiabetic agents. This study was designed to examine the phytochemical constituents and preliminary in vitro antidiabetic activity of Millingtonia hortensis L. and Mimusops elengi L., both known for their traditional medicinal applications.
Extracts prepared using different solvents were subjected to qualitative phytochemical analysis, revealing the presence of diverse secondary metabolites including flavonoids, phenolic compounds, alkaloids, tannins, saponins, glycosides, and terpenoids. The antidiabetic potential was assessed through inhibition assays targeting α-amylase and α-glucosidase enzymes. The results demonstrated that both plant extracts effectively inhibited these enzymes in a dose-responsive manner, indicating their potential role in moderating post-meal glucose levels.
The enzyme inhibitory activity observed may be linked to the presence of polyphenolic compounds, which are known to influence carbohydrate metabolism and oxidative balance. Overall, the findings highlight the therapeutic promise of these plant species as sources of bioactive compounds for diabetes management. Further detailed investigations, including compound isolation and biological validation, are warranted to confirm their efficacy.
Keywords Millingtonia hortensis L., Mimusops elengi L., phytochemical analysis, antidiabetic potential, enzyme inhibition, α-amylase, α-glucosidase, medicinal plants, polyphenols, in vitro study
Field Medical / Pharmacy
Published In Volume 8, Issue 2, March-April 2026
Published On 2026-04-17
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E-ISSN 2582-2160
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