Case Report: Marked Glycemic and Systemic Improvement Following Withdrawal of Intensive Pharmacotherapy with a Structured ~23-Hour Fasting (OMAD) Intervention in Long-standing Type 2 Diabetes

Author(s)	Dr. Kavitha P S, Dr. Ramana V Krishnan
Country	India
Abstract	Management of advanced type 2 diabetes mellitus (T2DM) often involves multi-drug pharmacotherapy targeting multiple metabolic pathways, including pancreatic insulin secretion, peripheral insulin sensitivity, and renal glucose excretion. Despite these approaches, a subset of patients continues to exhibit poor glycemic control, reflecting persistent metabolic dysfunction. Structured fasting protocols represent a metabolic strategy that may influence insulin dynamics, hepatic glucose output, and cellular energy utilization, thereby potentially improving glycemic control.
Keywords	Type 2 diabetic, trigonellin, fasting, chromium
Field	Biology
Published In	Volume 8, Issue 3, May-June 2026
Published On	2026-05-02

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