International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

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Volume 8 Issue 3
May-June 2026

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Borosilicate-Based Biomaterials: Compositional Tailoring, Degradation Behavior, and Biomedical Performance

Author(s) Ms. rajasri shikari, kumar Bikkanuri
Country India
Abstract Borosilicate-based biomaterials have emerged as a promising class of bioactive glasses due to their tunable degradation behavior and enhanced biological performance. Unlike conventional silicate bioactive glasses, these materials exhibit rapid dissolution owing to the presence of BO₃ and BO₄ structural units within the glass network, which significantly reduces network connectivity and enhances ion mobility [2], [6]. This study presents a comprehensive analysis of compositional tailoring, degradation mechanisms, and biomedical performance of borosilicate biomaterials. The influence of B₂O₃ content, modifier oxides, and microstructure on degradation kinetics and ion release is examined in detail. Results indicate that increasing boron content significantly enhances dissolution rates and bioactivity, leading to improved hydroxyapatite formation and osteogenic response [11], [12]. However, excessive boron release may affect cytocompatibility, necessitating optimized compositions [14]. Borosilicate biomaterials demonstrate excellent potential in bone regeneration, tissue engineering, and drug delivery applications due to their ability to release therapeutic ions that stimulate angiogenesis and cellular proliferation [4], [15].
Keywords Borosilicate bioactive glass; degradation kinetics; network connectivity; ion release; bone regeneration; tissue engineering; bioactivity.
Field Physics
Published In Volume 8, Issue 3, May-June 2026
Published On 2026-05-07
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E-ISSN 2582-2160
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