“Green Gold: From Algae to Pharmacy – Formulation and Evaluation of Spirulina as Nature’s Superfood in Nutraceutical Tablet Dosage Form”

Mayuri Sunil Bhamare; Kaustubh chhagan Aher; Mohit prakash Aher; Priti Devendra Barde; Fiza Javaroddin Maniyar; Mamta Abhiman Chaure; Priyanka Pramod Shirkande

“Green Gold: From Algae to Pharmacy – Formulation and Evaluation of Spirulina as Nature’s Superfood in Nutraceutical Tablet Dosage Form”

Author(s)	Ms. Mayuri Sunil Bhamare, Mr. Kaustubh chhagan Aher, Mr. Mohit prakash Aher, Ms. Priti Devendra Barde, Ms. Fiza Javaroddin Maniyar, Ms. Mamta Abhiman Chaure, Ms. Priyanka Pramod Shirkande
Country	India
Abstract	Spirulina has gained attention as a nutrient-dense microalgal ingredient for the development of oral nutraceutical dosage forms. The present study was designed to formulate spirulina tablets by the wet granulation method and to optimise batch performance through reformulation and post-compression evaluation. Five experimental batches (F1–F5) were prepared using spirulina powder with selected pharmaceutical recipients, and batch F3 was identified as the optimised formulation based on its overall physical characteristics and processing behavior. Reformulation results demonstrated improved powder flow after granulation, confirming the suitability of wet granulation for converting spirulina powder into compressible granules. The optimized F3 tablets showed satisfactory weight uniformity, adequate hardness, liability within acceptable limits, appropriate disintegration time, and high content uniformity, indicating a mechanically stable and pharmaceutically acceptable dosage form. These results provide credence to spirulina tablets' potential as a promising nutraceutical formulation and lay the groundwork for future scale-up and in vivo testing. Protein is the cornerstone of nutrition and the most crucial dietary item for a healthy lifestyle because it may be used as a fat or a carbohydrate in addition to its own protein value. For every 2.2 pounds of body weight, an adult needs one gram of usable protein. The complex protein molecule is made up of several interrelated components. Amino acids are the building components of proteins. 23 distinct amino acids are produced during the breakdown of protein during digestion. Amino acids fall into two categories: essential and non-essential. Eight amino acids have been found to be necessary for growth. Furthermore, without these eight essential amino acids, our body is unable to synthesise the remaining fifteen (non-essential) amino acids. The eight necessary amino acids are the building blocks of protein, a balanced diet, and even general wellness. Spirulina is considered a fantastic diet because it has antibacterial properties and is non-toxic. It can be broken down without the need of chemicals or processing since it lacks a cellulose cell wall. The range of digestibility is 83–84%. Spirulina is said to be rich in protein, vitamins, essential minerals, amino acids, EFA such gamma linoleic acid, and antioxidant pigments like carotene.
Keywords	Spirulina, wet granulation, tablet formulation, nutraceutical dosage form, preformulation, tablet evaluation, content uniformity.
Field	Medical / Pharmacy
Published In	Volume 8, Issue 3, May-June 2026
Published On	2026-05-18

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“Green Gold: From Algae to Pharmacy – Formulation and Evaluation of Spirulina as Nature’s Superfood in Nutraceutical Tablet Dosage Form”

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