Ajwaine Khorasani (Hyoscyamus Niger): Traditional Wisdom and Evidence-Based Pharmacological Applications

Author(s)	Prof. Dr. Salma Khatoon, Sabir Ahmed Momin, Safvana Faizabadi
Country	India
Abstract	Ajwaine Khorasani (Hyoscyamus Niger), is one of the most important and largest genera of the family Solanaceae, comprising about 84 genera and more than 3000 species. All Hyoscyamus species are rich sources of tropane alkaloids, mainly hyoscyamine and scopolamine. Phytochemical analyses have shown that Hyoscyamus species contain alkaloids, flavonoids, tannins, terpenes, saponins, carbohydrates, cardiac glycosides, and anthraquinones. These phytoconstituents exhibit a wide range of pharmacological activities, including antidiabetic, antioxidant, anticancer, insecticidal, antiasthmatic, antiallergic, antidiarrhoeal, antisecretory, hepatoprotective, antihyperuricemic, calcium channel-blocking, hypotensive, cardioprotective, antiparkinsonian, anticonvulsant, antidepressant, and anticholinergic effects, primarily attributed to the presence of tropane alkaloids.
Keywords	Hyoscyamus niger, Ajwaine Khorasani, Unani Medicine, Pharmacological Activities, Traditional Uses
Field	Medical / Pharmacy
Published In	Volume 8, Issue 3, May-June 2026
Published On	2026-05-20
DOI	https://doi.org/10.36948/ijfmr.2026.v08i03.79036

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