International Journal For Multidisciplinary Research

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Physicochemical Evaluation of Siddha Drug Soothaga Sanniku Nei

Author(s) Dr. Vedha B, Dr. Robin Jude P, Dr. Esakky Pandian G
Country India
Abstract Ethnomedical practices persist globally due to their effectiveness within regional populations. Standardizing and documenting these traditional practices are indispensable for integration into modern evidence-based healthcare systems. Soothaga Sanniku Nei (SSN) is a classical Siddha formulation prepared using cow's ghee along with nine crude herbal and mineral drugs. It is primarily indicated in traditional literature for complex gynecological conditions including Soothaga Sanni, Soothaga Vayu, and Azhal Noigal (which are analogous with modern nosology such as endometriosis, pelvic inflammatory disease, and PCOS). In this study, SSN was standardized following Pharmacopeial Laboratory of Indian Medicine (PLIM) guidelines. Physicochemical evaluation revealed an acid value of 87.10 mgKOH/g, a density of 1.113 g/ cm³, loss on drying at 7.90%w/w and a refractive index of 1.350. Heavy metals (Arsenic, Cadmium, Lead, Mercury), pesticide residues, specific foodborne pathogens (E. Coli, Salmonella, S. Aureus, P. Aeruginosa), and aflatoxins (B1, B2, G1, G2) were absent, ensuring compliance with AYUSH safety metrics. The standard parameters generated establish a baseline profile of Soothaga Sanniku Nei. Further studies are required to understand its mechanism of action and pharmacodynamic profile at molecular level.
Keywords Siddha Medicine, Soothaga Sanniku Nei, Standardization, Endometriosis, Physicochemical Analysis.
Field Medical / Pharmacy
Published In Volume 8, Issue 3, May-June 2026
Published On 2026-05-23
DOI https://doi.org/10.36948/ijfmr.2026.v08i03.79317
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