The GC MS Study of Poly Herbal Formulation Akkarakara Mezhugu Prepared As Per Siddha Literature

Author(s)	Dr. Gunaseelan P, Dr. Abin A, Dr. Antony Duraichi R
Country	India
Abstract	ABSTRACT: AkkarakaraMezhugu is a polyherbal Siddha formulation traditionally used to treat various conditions, including Erigunmam, Valigunmam, Naavinsurasurappu, and Thosathisurangal. This study performed a phytochemical analysis of the formulation using Gas Chromatography-Mass Spectroscopy (GC-MS). GC-MS analysis of a concentrated ethanol extract identified seven primary bioactive constituents, primarily fatty acids, fatty acid esters, and steroidal compounds. The identified compounds Oleic acid,10-Octadecanoic acid methyl ester, n-Hexadecanoic, Hexadecanoic acid methyl ester, 8-Octadecanoic acid, methyl ester (E), Stigmastane 3,6-dione, and 3-Eicosene (E). Their presence likely contributes to the formulation's efficacy in managing gastrointestinal disorders like Gunmamnoi. Further clinical and toxicological studies are recommended to fully validate its safety and mechanisms of action.
Keywords	Akkarakaramezhugu, Siddha medicine, GC-MS, Peptic ulcer
Field	Medical / Pharmacy
Published In	Volume 8, Issue 3, May-June 2026
Published On	2026-05-23
DOI	https://doi.org/10.36948/ijfmr.2026.v08i03.79375

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