International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 8, Issue 3 (May-June 2026) Submit your research before last 3 days of June to publish your research paper in the issue of May-June.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 8 Issue 3
May-June 2026

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

GC–MS-Based Metabolite Profiling and Evaluation of Antioxidant and Antimicrobial Activities of Litsea glutinosa (Lour.) C.B. Rob. Bark from Garo Hills, Meghalaya

Author(s) Ms. Bonchi D Marak, Dr. Amilia Nongbet
Country India
Abstract Litsea glutinosa (Lour.) C.B. Rob., a species in the family Lauraceae, is an underutilized medicinal plant having considerable ethnobotanical significance in traditional therapeutic practices. The current study was undertaken to assess the antioxidant and phytochemical characterization and investigate the pharmacological potential of L. glutinosa using the extract of root bark. The solvents of varying polarity were used for performing the phytochemical characterization, such as methanol (MeOH), ethanol (EtOH), hexane (Hex), ethyl acetate (Et Ac), and water (Aq). Initial phytochemical analysis has indicated a significant existence of phenolics and flavonoids, implying the substantial antioxidant capacity. The TPC was found to be highest in Et Ac solvent (0.165 ± 0.01 (mg GAE/g dry weight ± SD)) and the least in n-Hex (0.045 ± 0.04 (mg GAE/g dry weight ± SD)), whereas TFC was found to be highest in MeOH extract (283.5 ± 0.001 (mg QE/g dry weight ± SD)) and lowest in (47.8 ± 0.001 (mg QE/g dry weight ± SD)) quantified using the Folin-Ciocalteu reagent and AlCl₃ colorimetric techniques, respectively, suggesting a significant presence of bioactive phytochemicals. Moreover, the antioxidant study using DPPH radical scavenging activity was found to be highest in the MeOH extract with the IC50 value of 15.26 µg/ml and the least in the Hex extract with the IC50 value of 99.72 µg/ml. Furthermore, GC-MS profiling of the bark extract revealed a wide spectrum of bioactive components, viz., naphthalene; myrtenyl angelate; Z,Z-6,28-heptatriactontadien-2-one; ButanoicAcid,2-Methyl-,2-Methyl-2-Propenyl Ester; Hentriacontane; heptacosanoic acid, 25-Methyl-, Methyl Ester, etc., many of which were previously linked to pharmacological activity in the past. These compounds highlighted the therapeutic potentiality of L. glutinosa, particularly in its anti-inflammatory, antibacterial, antioxidant, and potentially anticancer qualities. In addition, the FTIR analysis for methanol extract has revealed various different types of functional groups, viz., alcohols, phenols, alkanes, alkyls, carboxylic acids, esters, ethers, and halo compounds. The Minimum Inhibition Concentration (MIC) performed using 2 bacterial and 2 fungal strains has shown an MIC % of inhibition variations in 3 concentrations taken, i.e., 1000-250 µg/ml, showing the potentiality of inhibiting the growth of bacteria and fungi tested. The results of this study provide support to the traditional applications of L. glutinosa bark and encourage more research into the plant as a possible source of new bioactive compounds to be used in pharmaceutics.
Keywords Litsea glutinosa (Lour.) C.B. Rob., medicinal herb, phytochemistry, GC-MS, FTIR.
Field Biology
Published In Volume 8, Issue 3, May-June 2026
Published On 2026-05-29
DOI https://doi.org/10.36948/ijfmr.2026.v08i03.79706
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 8 Isu 3Cover Page Vol 8 Isu 2Cover Page Vol 8 Isu 2

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9687-828-838 editor@ijfmr.com
Powered by Sky Research Publication and Journals