International Journal For Multidisciplinary Research

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A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 8, Issue 5 (September-October 2026) Submit your research before last 3 days of October to publish your research paper in the issue of September-October.

Efficacy and Safety of a Mool Health’s Personalized Ayurvedic Gut Health Regimen in Management of Functional Constipation (FC) and irritable bowel syndrome with constipation (IBS-C): A Clinical Evaluation

Author(s) Dr. Khemraj Mourya, Dr. Dipti Gupta, Dr. Devesh Kumar, Dr. Yash Gangal
Country India
Abstract Functional constipation (FC) and irritable bowel syndrome with constipation (IBS-C) are common gastrointestinal disorders that significantly impair quality of life. This study evaluated the efficacy and safety of a personalized Ayurvedic gut health regimen developed by Mool Health in adults with FC or IBS-C. A 28-day clinical trial was conducted at Tulsi Multispecialty Hospital, Delhi, India, involving 40 adult Participants aged 18–60 years. Participants received individualized Ayurvedic therapy tailored according to baseline symptom severity determined through an online diagnostic assessment. Efficacy was evaluated using a Visual Analog Scale (VAS), Patient Assessment of Constipation-Symptoms (PAC-SYM), and the Bristol Stool Form Scale, while safety was monitored through adverse event reporting and vital sign assessment.
All participants (FC: 24; IBS-C: 16) completed the 28-day study with no dropouts. Based on Clinical response rate of the participants of VAS score assessment at the end of the study, (95%) reported reduction in constipation, (90.5%) in acidity, (77.7%) in bloating, (89.2%) in gas, (90%) in stress, and (70%) in Sleeplessness symptoms. PAC-SYM scores demonstrated significant reductions in abdominal discomfort (-80.4%), rectal burning (-76.2%), and hard stools (-78.9%). Stool frequency was lowered from 2.53 ± 0.43 to 1.38 ± 0.27 movements/day signifying the improvement in gut health. All participants had transitioned from constipated stool types (Types 1–2) to normal forms (Types 3–4) by day 28. Subgroup analysis revealed that FC participants had a higher frequency of Type 4 stools (66.7%), whereas the IBS-C group showed greater improvement in bloating (-83.33%) and acidity (-83.93%). No serious adverse events were observed.
These findings from this explorative study suggest that Mool Health’s personalized regimen is a safe and holistic intervention in management of FC and IBS-C.
Keywords Functional constipation, IBS-C, Ayurvedic intervention, Probiotic, Gut health, Clinical trial, Personalized therapy
Field Medical / Pharmacy
Published In Volume 8, Issue 4, July-August 2026
Published On 2026-07-22
DOI https://doi.org/10.36948/ijfmr.2026.v08i04.83904

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