International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 8, Issue 4 (July-August 2026) Submit your research before last 3 days of August to publish your research paper in the issue of July-August.
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Volume 8 Issue 4
July-August 2026

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Recent Advances in Hybrid Ethosomes Based Metallic Nanoparticles for Antimicrobial Activity

Author(s) Ms. Mayuri Mahadev More, Pooja Balasaheb Varpe
Country India
Abstract Hybrid nano-delivery systems that combine ethosomes with metallic nanoparticles signify an exciting advancement in antimicrobial therapy. Ethosomes, due to their phospholipid-based vesicular structure, enable deep dermal penetration and enhance drug bioavailability. Meanwhile, metallic nanoparticles like silver or zinc oxide offer inherent antimicrobial properties through the generation of reactive oxygen species and disruption of membranes. This synergistic combination boosts therapeutic effectiveness by improving drug permeation while also delivering direct bactericidal effects, thus addressing the shortcomings of traditional formulations. Recent studies underscore their potential in tackling multidrug-resistant pathogens, lowering dosage requirements, and reducing systemic toxicity. Additionally, the hybrid method provides flexibility for encapsulating both hydrophilic and lipophilic agents, making it suitable for a wide range of pharmaceutical and cosmeceutical applications. Consequently, this dual-functional system establishes a strong foundation for next-generation antimicrobial strategies, aligning with global priorities for innovative solutions to combat resistant infections. Future research should focus on optimizing formulation stability, scalability, and long-term safety to facilitate clinical translation. Moreover, regulatory standardization and in vivo validation will be crucial to fully realize their potential in mainstream therapeutic applications.
Keywords Ethosemes, Metallic nanoparticle, Hybrid nano-delivery system, Antimicrobial resistance, Drug permeation
Field Biology > Zoology
Published In Volume 8, Issue 4, July-August 2026
Published On 2026-08-04
DOI https://doi.org/10.36948/ijfmr.2026.v08i04.84070
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CrossRef DOI prefix of IJFMR is 10.36948/ijfmr

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