International Journal For Multidisciplinary Research
E-ISSN: 2582-2160
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Impact Factor: 9.24
A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal
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Volume 8 Issue 4
July-August 2026
Indexing Partners
How Superparamagnetic Nanoparticles are Revolutionizing the Global Fight Against Cancer
| Author(s) | Ms. Tripti Kumar |
|---|---|
| Country | India |
| Abstract | The persistent threat of global cancer necessitates novel approaches in treating this disease by finding therapies to overcome toxicity of today's surgery, chemotherapy and radiation. Magnetically guided nanotherapeutics have emerged as one of the prominent candidates as the next generation site-specific and less-invasive method. Usually based on bioinert iron oxide (magnetite and maghemite) superparamagnetic nanoparticles that can be targeted at any area of interest by using an external magnetic field gradient, this approach is useful for a variety of applications from passive and active biochemical targeting to magnetic hyperthermia (induced cell death using time-varying magnetic field) to T2 contrast agents for MRI applications that represent theranostics by integrating therapy and diagnosis. However, translation of this approach to clinical setting continues to face issues with, inter alia, the immune response from the reticuloendothelial system, poor external magnetic field depth penetrability, potential long term toxicity issues, manufacturing guidelines. I’ll review the behaviour of magnetically targeted nanoparticles within tumour microenvironment, and how they may fit into personalized oncology platforms and conclude that magnetic targeting holds promise as a promising paradigm for a high efficacy, low-toxicity therapeutic solution |
| Keywords | Superparamagnetic Iron Oxide Nanoparticles (SPIONs), Magnetic Drug Targeting, Cancer Nanomedicine, Magnetic Hyperthermia, Theranostics |
| Field | Biology > Medical / Physiology |
| Published In | Volume 8, Issue 4, July-August 2026 |
| Published On | 2026-07-24 |
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E-ISSN 2582-2160
CrossRef DOI prefix of IJFMR is 10.36948/ijfmr
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