International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 8, Issue 4 (July-August 2026) Submit your research before last 3 days of August to publish your research paper in the issue of July-August.
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Volume 8 Issue 4
July-August 2026

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"Translating Herbal Potency into Dosage Form: Development and Evaluation of Moringa Oleifera Enriched Lozenges"

Author(s) Miss Vaishnavi Bharti, Dr. Avinash Jiddewar, Prof. Dr. Akshay Kasambe, Miss Anushka Akkalwar, Miss Laxmi Kawale, Miss Reshma Kale, Mr Akib Khan
Country India
Abstract The present investigation focuses on the development of a multifunctional Moringa oleifera lozenge designed not only as a conventional throat soothing preparation but also as a localized phytochemical delivery platform for oral mucosal therapy. The study uniquely emphasizes the natural isothiocyanates, flavonoids, and enzyme-activated bioactive compounds present in Moringa oleifera, which upon gradual dissolution in saliva may create a sustained antimicrobial and antioxidant microenvironment within the oral cavity. In addition, the mucilage-like nature of Moringa phytoconstituents was explored for its potential to enhance mucosal residence time by forming a thin protective bioadhesive layer over irritated oral tissues.
The optimized lozenge formulation demonstrated excellent physicochemical stability with uniform drug distribution and controlled release behaviour, achieving nearly complete phytoconstituent release within 30 minutes while maintaining structural integrity and acceptable mechanical strength. The formulation further addressed one of the major formulation challenges associated with Moringa oleifera—its inherent bitterness—through successful taste balancing, improving palatability and patient compliance.
The developed system highlights the untapped potential of Moringa oleifera as a modern orotransmucosal phytopharmaceutical capable of delivering both therapeutic and nutritional benefits simultaneously. The study establishes a novel approach toward integrating bioadhesive herbal delivery with sustained phytochemical activation, offering promising applications in oral infections, throat irritation, mucosal inflammation, and supportive immune care.
Field Medical / Pharmacy
Published In Volume 8, Issue 4, July-August 2026
Published On 2026-07-27
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E-ISSN 2582-2160
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CrossRef DOI prefix of IJFMR is 10.36948/ijfmr

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