International Journal For Multidisciplinary Research

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Volume 8 Issue 4
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PCOS to PMOS: Revisiting a Multisystem Disorder Through an Individualised Lens

Author(s) Dr. Neeta Jain, Dr. Niharika Jain, Dr. Ankita Jain
Country India
Abstract Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders affecting women of reproductive age and is increasingly recognised as a complex condition extending beyond reproductive dysfunction. In 2026, an international consensus process proposed the term Polyendocrine Metabolic Ovarian Syndrome (PMOS) to reflect better the endocrine, metabolic, reproductive, and psychosocial dimensions of the disorder. This narrative review explores the evolving PMOS paradigm, with particular emphasis on disease heterogeneity, psychological burden, stress-related neuroendocrine dysregulation, and the role of lifestyle and mind-body interventions in long-term management. The review highlights the bidirectional relationship between psychological distress and metabolic dysfunction, including the potential involvement of hypothalamic-pituitary-adrenal axis dysregulation in disease expression. The implications of the PMOS framework for individualised care are discussed, with particular attention to the relevance of constitutional homoeopathic assessment as a patient-centred approach that considers physical, emotional, and behavioural characteristics. Current evidence from reviews, observational studies, case reports, and a pilot randomised controlled trial suggests growing interest in homoeopathic approaches to PCOS/PMOS. The transition from PCOS to PMOS reflects a broader understanding of the disorder as a heterogeneous multisystem condition and supports the exploration of individualised and integrative approaches to care. Further high-quality research is required to clarify the role of constitutional homoeopathic assessment within PMOS management.
Keywords Keywords: Polyendocrine Metabolic Ovarian Syndrome (PMOS); Polycystic Ovary Syndrome (PCOS); Homoeopathy; Individualisation; Integrative Medicine; Lifestyle Medicine.
Field Medical / Pharmacy
Published In Volume 8, Issue 4, July-August 2026
Published On 2026-07-27
DOI https://doi.org/10.36948/ijfmr.2026.v08i04.84634
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