International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 8, Issue 4 (July-August 2026) Submit your research before last 3 days of August to publish your research paper in the issue of July-August.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 8 Issue 4
July-August 2026

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

Preparation and Characterization of Microcrystalline Cellulose from Nata de Ganyong as an Excipient for Capsule Product

Author(s) Dr. Ira Adiyati Rum, Dr. Soni Muhsinin
Country Indonesia
Abstract One imported raw material widely used as an excipient (filler-binder) in tablet manufacturing is microcrystalline cellulose (MCC). The microcrystalline cellulose commonly found on the market is widely known by the trade name Avicel. Avicel is a relatively expensive additive. In accordance with the Regulation of the Minister of Health of the Republic of Indonesia No. 87 of 2013 regarding the roadmap for pharmaceutical raw material development, efforts to achieve self-sufficiency using biological resources are being undertaken to address the high costs of importing pharmaceutical raw materials. Indonesia’s greatest opportunity lies in developing a biotechnology-based industry, as this type of industry does not rely on upstream chemical industry products but allows for direct production within a bioreactor or fermenter. Therefore, this study aims to produce a tablet excipient from nata de ganyong. This study employs an experimental laboratory method. The first stage involves the preparation and botanical identification of Canna edulis (ganyong) tubers. The second stage entails processing the Canna edulis tubers into nata de ganyong via fermentation using Acetobacter xylinum, followed by quality evaluation of the resulting nata (including organoleptic tests, thickness measurement, and analysis of moisture content and yield). Subsequently, microcrystalline cellulose is isolated from the nata de ganyong. This is followed by an evaluation of the MCC powder and the formulation of capsules using the nata de ganyong-derived MCC as an excipient. Capsule evaluations included tests for weight uniformity, disintegration time, and hygroscopicity; all results were satisfactory and met pharmaceutical standards.
Keywords capsule, nata, fermentation, Acetobacter xylinum, microcrystalline cellulose (MCC)
Field Medical / Pharmacy
Published In Volume 8, Issue 4, July-August 2026
Published On 2026-08-04
DOI https://doi.org/10.36948/ijfmr.2026.v08i04.85111
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI prefix of IJFMR is 10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9687-828-838 editor@ijfmr.com
Powered by Sky Research Publication and Journals