Clinical and Haematological Improvement Following a 90-Day Oral Iron Supplementation Regimen in Adults with Iron Deficiency Anemia - A Prospective Real-World Observational Study

Chetan Savaliya; Shridhar Pandya; Prerana Patil; Shivangi Dave; Vaishnavi Ghodke

doi:10.36948/ijfmr.2026.v08i04.85447

Clinical and Haematological Improvement Following a 90-Day Oral Iron Supplementation Regimen in Adults with Iron Deficiency Anemia - A Prospective Real-World Observational Study

Author(s)	Dr. Chetan Savaliya, Dr. Shridhar Pandya, Prerana Patil, Shivangi Dave, Vaishnavi Ghodke
Country	India
Abstract	Introduction: Iron deficiency anemia (IDA) is a prevalent nutritional disorder worldwide and a major contributor to fatigue, impaired physical performance, reduced quality of life, and increased morbidity. Although oral iron supplementation remains the standard first-line therapy for uncomplicated IDA, treatment outcomes may be affected by poor gastrointestinal tolerability, limited absorption, and adherence challenges. This study evaluated the clinical and hematological outcomes of a structured 90-day oral iron supplementation regimen in adults with moderate to severe IDA. Method: Fifty adults with moderate to severe IDA completed a 90-day supplementation protocol comprising one oral iron tablet twice daily along with dietary counselling. Hemoglobin (Hb), serum iron, total iron-binding capacity (TIBC), and transferrin saturation (TSAT) were assessed at baseline and Day 90. Clinical symptoms, including generalized weakness, hair loss, and dizziness, were monitored along with treatment compliance and adverse events. Results: Significant improvements were observed across all hematological parameters following supplementation (p<0.0001). Mean Hb increased from 8.82 ± 0.60 g/dL to 13.42 ± 0.50 g/dL, with substantial improvements in serum iron and TSAT and normalization of TIBC levels. Complete resolution of baseline clinical symptoms was reported in all participants. No treatment-related adverse events were observed, indicating good tolerability. Conclusion: A 90-day oral iron supplementation regimen demonstrated significant hematological recovery, symptomatic improvement, and favourable tolerability in adults with moderate to severe IDA. These findings provide real-world evidence supporting its potential role as an effective nutritional approach for IDA management.
Keywords	Iron deficiency anemia, Hemoglobin, serum iron, transferrin saturation, Total Iron-Binding Capacity.
Field	Medical / Pharmacy
Published In	Volume 8, Issue 4, July-August 2026
Published On	2026-08-10
DOI	https://doi.org/10.36948/ijfmr.2026.v08i04.85447

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Clinical and Haematological Improvement Following a 90-Day Oral Iron Supplementation Regimen in Adults with Iron Deficiency Anemia - A Prospective Real-World Observational Study

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