International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 8, Issue 4 (July-August 2026) Submit your research before last 3 days of August to publish your research paper in the issue of July-August.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 8 Issue 4
July-August 2026

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

A Matrix-Reduced Whole-Cactus Approach to San Pedro: A Two-Stage Framework for Selective Reduction of the Mucilage–Polysaccharide Matrix

Author(s) Dr. Elias Rubenstein
Country United States
Abstract San Pedro preparations derived from Echinopsis pachanoi contain mescaline together with minor alkaloids, soluble metabolites, mucilage, colloids, suspended solids, and other cactus-derived constituents. This physical matrix contributes substantially to the volume, viscosity, and material burden of conventional aqueous preparations while remaining chemically distinct from the principal low-molecular-weight alkaloids. This article proposes a matrix-reduced whole-cactus approach that separates primary botanical extraction from subsequent physical refinement. Fresh cactus tissue is extracted in mildly acidic water and filtered to remove coarse structural material. High-strength food-grade ethanol is then added to the retained aqueous extract to induce aggregation of an ethanol-responsive polymer-rich fraction, which is removed by a second filtration or decantation before the ethanol is reduced and the preparation returned to a defined aqueous volume. The process remains continuously derived from the original cactus extract without isolating or recombining mescaline. Performance is evaluated by paired mass balance, comparing mescaline recovery, minor-alkaloid retention, broader phytochemical continuity, dry matter, polysaccharide content, suspended solids, viscosity, and separated matrix mass. The framework provides a simple and experimentally testable intermediate between conventional cactus decoction and molecular mescaline isolation and establishes post-extraction matrix reduction as an independent variable in botanical preparation technology.
Keywords San Pedro, Echinopsis pachanoi, Trichocereus pachanoi, Huachuma, mescaline, cactus mucilage, polysaccharides, hydrocolloids, matrix reduction, whole-cactus extraction, post-extraction separation.
Field Chemistry > Pharmacy
Published In Volume 8, Issue 4, July-August 2026
Published On 2026-08-16
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI prefix of IJFMR is 10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9687-828-838 editor@ijfmr.com
Powered by Sky Research Publication and Journals