Social Impact of Thalassemia: Assessing Social Well-being and Quality of Life

Author(s)	Mr. Akhilesh Kumar Yadav, Ms. Kirti Kumari
Country	India
Abstract	A genetic blood condition called thalassemia is linked to a decrease in hemoglobin in red blood cells (RBCs), which in turn results in less oxygen getting to the body's cells. Alpha-globin and beta-globin, components of hemoglobin, the protein that carries oxygen in the blood, are produced defectively in thalassemia, a hereditary condition. The Greek terms "Thalassa" (sea) and "Haema" (blood) are the origin of the name. Alpha-thalassemia and beta-thalassemia are the two primary forms. The Thalassemia National Federation observed Thalassemia Day for the first time on May 8, 1994. The study found that children with moderate alpha-thalassemia are naturally protected from malaria-related anemia. Eight hundred children participated in the study, which was carried out in Papua New Guinea. In addition to the high prevalence of alpha-thalassemia in youngsters, malaria is endemic in this area. Globally, thalassemia is common; in 2013, it caused 25,000 fatalities. The Mediterranean, Italy, Greece, Turkey, West Asia, North Africa, South Asia, and Southeast Asia have the highest rates. Children with β-thalassemia major, the most severe type, must get frequent blood transfusions to survive.
Keywords	Thalassemia, Hemoglobinopathies, Bone Marrow Transplant, Gene Therapy, Gene therapy, Hypoxia
Published In	Volume 8, Issue 5, September-October 2026
Published On	2026-09-09

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