International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 8, Issue 5 (September-October 2026) Submit your research before last 3 days of October to publish your research paper in the issue of September-October.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 8 Issue 5
September-October 2026

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

Detection of Nontuberculous Mycobacteria by MALDI-TOF MS and Its Co-infection with Mycobacterium Tuberculosis

Author(s) Mahima Chouhan, Dr. Jayant Ramawat, Dr. Prabhu Prakash
Country India
Abstract Introduction: Coinfection of MTB complex with NTM is increasingly recognised in TB endemic countries, which may remain undiagnosed or coexist with pulmonary TB, resulting in diagnostic and therapeutic challenges. Methods: An observational study was conducted in a tertiary care centre, which included suspected NTM pulmonary disease patients’ LJ culture isolates. Patients were of all age groups and both sexes. Detection of co-infections was via CBNAAT and/or LPA and MALDI-TOF Mycobacterial/Nocardia Kit. Results: Among 55 patients with suspected NTM pulmonary disease, 10 NTM isolates (18.2%; 10/55) were identified by MALDI-TOF MS. The identified species were Mycobacterium kansasii (n=4; 40%), Mycolicibacterium fortuitum (n=4; 40%), and Mycolicibacterium wolinskyi (n=2; 20%). MTB–NTM coinfection was detected in 4/10 (40.0%) NTM-positive patients, corresponding to 4/55 (7.3%) of the total study population. Of these four coinfected patients, two were MTB-positive by CBNAAT and rifampicin-sensitive, while the remaining two were positive by first-line LPA and were sensitive to both rifampicin and isoniazid. Among the coinfected patients, M. fortuitum accounted for 2/4 (50%), while M. kansasii and M. wolinskyi accounted for 1/4 (25%) each. Conclusion: NTM infection along with MTB–NTM coinfection was low among TB-suspected patients. Identification by the MALDI-TOF MS of suspected NTM pulmonary disease diagnosis enables rapid and accurate species identification and improves recognition of NTM infections in TB-endemic areas and potentially reduces morbidity.
Keywords Tuberculosis, Nontuberculous mycobacteria, MTB–NTM coinfection, MALDI-TOF MS, Mycobacterium fortuitum, Mycobacterium kansasii, Mycobacterium wolinskyi.
Field Biology > Medical / Physiology
Published In Volume 8, Issue 5, September-October 2026
Published On 2026-10-18
DOI https://doi.org/10.36948/ijfmr.2026.v08i05.87530
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI prefix of IJFMR is 10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9687-828-838 editor@ijfmr.com
Powered by Sky Research Publication and Journals