Individualized Homoeopathic Management in Atopic Dermatitis: A Systematic Review of Clinical Outcomes, Disease Severity Indices, and Health-Related Quality of Life Parameters

Pankaj N Lathiya; Rupali V Ahire; Mahesh B Dusane; Anjani Patel

doi:10.36948/ijfmr.2026.v08i05.87705

Individualized Homoeopathic Management in Atopic Dermatitis: A Systematic Review of Clinical Outcomes, Disease Severity Indices, and Health-Related Quality of Life Parameters

Author(s)	Dr. Pankaj N Lathiya, Dr. Rupali V Ahire, Dr. Mahesh B Dusane, Dr. Anjani Patel
Country	India
Abstract	Background: Atopic dermatitis (AD) is an inflammatory skin condition. AD causes pruritus (itching), disruption to sleep, and causes visible lesions. These effects affect the quality of life of the sufferer. Individualized homeopathy is used by some sufferers, however the available data is scarce and in need of better evaluation. Goal: This study aims to identify, evaluate, and integrate data on individualized homeopathic treatment of AD related to symptom severity and quality of life. Methods: We performed a structured literature search of PubMed/MEDLINE, literature published on the publisher’s sites, DOI/Crossref metadata, and scholarly web indexing. We followed the PRISMA 2020 reporting guidelines. There were no audit records available at the database export level, so the screening workflow was represented by a PRISMA log that included 214 records, with 58 removed during the removal of duplicates, 156 records screened, 21 reports reviewed, 14 reported excluded, and 7 included reports, representing 6 studies; 3 of these studies provided data on the severity of individualized homeopathic treatment to be synthesized. Results: This evidence consists of small placebo-controlled studies, 1 prospective uncontrolled study, 1 selected case series, a non-randomized comparative pediatric cohort study with long-term follow up, and preliminary data. The placebo-controlled study published in 2009 found no difference in the treatment of AD and individualized homeopathic treatment. The preliminary data published in 2022 was also unclear in its findings, and published data in 2023 found a significant 6 months PO-SCORAD (a symptom score) with individualized homeopathy, and no significant effect on the DLQI (quality of life) or ADBSA (severity) scores. The long-term study of pediatric cohorts found no superiority of individualized homeopathic treatment over conventional treatment. An exploratory three-study synthesis with a random effects model yielded Hedges’ g = -0.35 (95% CI -1.59 to 0.89; p = 0.584; I² = 93.0%), which was no significant effect, and remained highly heterogeneous. Conclusion: Presently, the evidence is inconsistent and methodologically limited. A positive recent trial requires an independent replication, but the overall evidence is insufficient to make a definitive conclusion regarding the efficacy.
Keywords	Atopic dermatitis; atopic eczema; individualized homeopathy; SCORAD; PO-SCORAD; quality of life; systematic review.
Field	Medical / Pharmacy
Published In	Volume 8, Issue 5, September-October 2026
Published On	2026-09-12
DOI	https://doi.org/10.36948/ijfmr.2026.v08i05.87705

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Individualized Homoeopathic Management in Atopic Dermatitis: A Systematic Review of Clinical Outcomes, Disease Severity Indices, and Health-Related Quality of Life Parameters

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