International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 8, Issue 5 (September-October 2026) Submit your research before last 3 days of October to publish your research paper in the issue of September-October.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 8 Issue 5
September-October 2026

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

Evaluation of the Nephroprotective Effects of Methanolic Extract of Hygrophila Auriculata (Neermulli Plant)

Author(s) Ms. Anjali A, Dr. Gomathy G
Country India
Abstract ABSTRACT
Nephrotoxicity remains a major clinical concern associated with exposure to drugs, environmental pollutants, and oxidative stress–inducing agents, leading to progressive renal impairment. The present study aimed to Evaluate the Renoprotective potential of Neermulli extract ( Hygrophila auriculata )against Nephrotoxicant-induced cellular damage in vero cells. The Methanolic extract of Neermuli Plant was prepared and subjected to preliminary phytochemical screening to identify bioactive constituents.
Medicinal plants have been extensively investigated for their therapeutic potential against renal disorders due to their rich content of bioactive phytochemicals such as flavonoids, phenolics, alkaloids, and terpenoids. Vero cells were cultured under standard conditions and exposed to a known Nephrotoxicant to induce oxidative stress–mediated cytotoxicity. The protective efficacy of the extract was assessed through cell viability (MTT assay), Estimation of antioxidant enzymes including superoxide dismutase (SOD) and Catalase (CAT), and measurement of lipid peroxidation (LPO) levels.Numerous studies have reported the Renoprotective effects of plant extracts against Nephrotoxicant-induced oxidative damage through antioxidant, anti-inflammatory, and anti-apoptotic mechanisms.Nephrotoxicity refers to renal dysfunction caused by exposure to drugs, chemicals, or environmental pollutants that adversely affect kidney structure and function. The observed Renoprotective activity may be attributed to the antioxidant and free radical scavenging properties of its phytoconstituents. Neermuli extract exhibits significant protective effects against Nephrotoxicant-induced cellular injury in Vero cells, suggesting its potential as a natural therapeutic agent for preventing oxidative stress–mediated renal damage.
Keywords Neermuli, Nephrotoxicant, Antioxidant enzymes, Free radical
Field Biology > Bio + Chemistry
Published In Volume 8, Issue 5, September-October 2026
Published On 2026-09-20
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI prefix of IJFMR is 10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9687-828-838 editor@ijfmr.com
Powered by Sky Research Publication and Journals