International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 8, Issue 5 (September-October 2026) Submit your research before last 3 days of October to publish your research paper in the issue of September-October.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 8 Issue 5
September-October 2026

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

Effect of gut microbiome and outcome of gut dysbiosis on skin health: Gut-Skin axis

Author(s) Ms. Lakkshaya Kuppusamy Gurumurthy
Country India
Abstract Recent advances in metagenomics and immunology have revealed the gut-skin axis, a bidirectional communication where the gastrointestinal microbiota influences skin homeostasis and immune response. This axis operates through systemic circulation of microbial metabolites such as short chain fatty acids (SCFAs), neuroendocrine signaling and modulation of systemic inflammation. The skin and the gut represent two of the body’s most significant ecological niche, hosting complex and dense microbiomes. Any disruption in the normal gut microbiome termed dysbiosis can impair the skin health. Dysbiosis can alter gut barrier permeability (leaky gut) and allow pathogens and its metabolites to enter the blood stream. The proinflammatory cytokines that enter systemic circulation migrate to the skin, where they alter the cutaneous environment and trigger or exacerbate several inflammatory pathologies, psoriasis, atopic dermatitis (AD), acne vulgaris (AV) and rosacea. Although multiple studies have demonstrated an association between gut dysbiosis and various skin dermatoses, the underlying mechanisms by which these alterations influence skin health remain incompletely understood. This review summarizes existing data on microbial ecology and its functional contribution to host health and homeostasis. While exploring potential mechanisms links between gut-skin axis and associated diseases. Furthermore, we review current and emerging interventions targeting and modulating gut microbiomes, and discuss their therapeutic potential in skin disorders.
Keywords gut microbiota, skin microbiome, probiotics, prebiotics, synbiotics, postbiotics, atopic dermatitis, psoriasis, acne vulgaris, and chronic urticaria.
Field Medical / Pharmacy
Published In Volume 8, Issue 5, September-October 2026
Published On 2026-09-30
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI prefix of IJFMR is 10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9687-828-838 editor@ijfmr.com
Powered by Sky Research Publication and Journals