International Journal For Multidisciplinary Research
E-ISSN: 2582-2160
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Volume 8 Issue 5
September-October 2026
Indexing Partners
Retroperitoneal Schwannoma: A Surgical Challenge in an Unusual Location
| Author(s) | Dr. Jameel Akhter, Dr. Veni N |
|---|---|
| Country | India |
| Abstract | Background: Schwannomas are benign nerve sheath tumours that rarely occur in the retroperitoneum, where their deep and confined anatomical location can make preoperative diagnosis and surgical access challenging. Case presentation: A 38-year-old woman presented with left-flank abdominal pain and intermittent dyspepsia, with left-flank tenderness on examination and no palpable mass. Investigations/diagnosis: Magnetic resonance imaging demonstrated a well-defined, heterogeneous, T2-hyperintense presacral soft-tissue lesion at the S1–S2 level, and contrast-enhanced computed tomography similarly identified a presacral mass; a neoplastic soft-tissue mass lesion was considered, and the preoperative diagnosis was a retroperitoneal mass of the presacral region. Management: The patient underwent laparoscopic excision, which revealed a 6×5×5 cm highly vascular retroperitoneal mass at the mesorectum abutting the presacral fascia, dissected through difficult tissue planes after lateralising the rectum; the mass was retrieved via a small Pfannenstiel incision. Histopathology showed a cellular spindle-cell lesion with interlacing fascicles, hyalinised vessels, and rare mitoses, favouring schwannoma, and immunohistochemistry confirmed diffuse S100 and SOX10 positivity with retained H3K27me3 expression, consistent with a benign schwannoma. Outcome: The postoperative course was uneventful, and the patient was discharged on the third postoperative day. Conclusion: This case highlights the diagnostic and technical challenges posed by a presacral retroperitoneal schwannoma closely related to the mesorectum, and demonstrates that laparoscopic excision is feasible with careful identification of tissue planes and rectal lateralisation. |
| Keywords | Retroperitoneal schwannoma, schwannoma, retroperitoneal tumor, presacral space, laparoscopic excision, immunohistochemistry. |
| Field | Medical / Pharmacy |
| Published In | Volume 8, Issue 5, September-October 2026 |
| Published On | 2026-10-10 |
| DOI | https://doi.org/10.36948/ijfmr.2026.v08i05.88638 |
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E-ISSN 2582-2160
CrossRef DOI prefix of IJFMR is 10.36948/ijfmr
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