International Journal For Multidisciplinary Research

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A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 8, Issue 5 (September-October 2026) Submit your research before last 3 days of October to publish your research paper in the issue of September-October.

Retroperitoneal Schwannoma: A Surgical Challenge in an Unusual Location

Author(s) Dr. Jameel Akhter, Dr. Veni N
Country India
Abstract Background: Schwannomas are benign nerve sheath tumours that rarely occur in the retroperitoneum, where their deep and confined anatomical location can make preoperative diagnosis and surgical access challenging.
Case presentation: A 38-year-old woman presented with left-flank abdominal pain and intermittent dyspepsia, with left-flank tenderness on examination and no palpable mass.
Investigations/diagnosis: Magnetic resonance imaging demonstrated a well-defined, heterogeneous, T2-hyperintense presacral soft-tissue lesion at the S1–S2 level, and contrast-enhanced computed tomography similarly identified a presacral mass; a neoplastic soft-tissue mass lesion was considered, and the preoperative diagnosis was a retroperitoneal mass of the presacral region.
Management: The patient underwent laparoscopic excision, which revealed a 6×5×5 cm highly vascular retroperitoneal mass at the mesorectum abutting the presacral fascia, dissected through difficult tissue planes after lateralising the rectum; the mass was retrieved via a small Pfannenstiel incision. Histopathology showed a cellular spindle-cell lesion with interlacing fascicles, hyalinised vessels, and rare mitoses, favouring schwannoma, and immunohistochemistry confirmed diffuse S100 and SOX10 positivity with retained H3K27me3 expression, consistent with a benign schwannoma.
Outcome: The postoperative course was uneventful, and the patient was discharged on the third postoperative day.
Conclusion: This case highlights the diagnostic and technical challenges posed by a presacral retroperitoneal schwannoma closely related to the mesorectum, and demonstrates that laparoscopic excision is feasible with careful identification of tissue planes and rectal lateralisation.
Keywords Retroperitoneal schwannoma, schwannoma, retroperitoneal tumor, presacral space, laparoscopic excision, immunohistochemistry.
Field Medical / Pharmacy
Published In Volume 8, Issue 5, September-October 2026
Published On 2026-10-10
DOI https://doi.org/10.36948/ijfmr.2026.v08i05.88638

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