International Journal For Multidisciplinary Research

E-ISSN: 2582-2160     Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 6 Issue 1 January-February 2024 Submit your research before last 3 days of February to publish your research paper in the issue of January-February.

Green Synthesis of Silver Nanoparticles from Bark Extract to Detect Anti Ulcer Activity in Swiss Albino Rats

Author(s) Kalpana p Ghoshal, Ajay Ghatole
Country India
Abstract The anti-ulcer activity of Butea monosperma silver nanoparticles (SNBM) was estimated in Swiss albino rats using ulcers caused by histamine, drugs, and ethanol. The effects of the SNBM at the doses of 300 and 550 mg/kg per os (p.o.) were compared with those of the reference pharmaceuticals, famotidine (35 mg/kg b.w.), and revealed substantial safeguards against ulcers generated by indomethacin and histamine. Additionally, the extract demonstrated excellent resistance against stomach ulcers brought on by ethanol. In addition, in ethanol-induced stomach ulceration, SNBM drastically lowered the spike in lipid peroxide level [(Thiobarbituric acid reactive substances (TBARS)] and restored the altered glutathione level. According to the study, SNBM demonstrates anti-ulcer efficacy by enhancing the gastric mucosa's antioxidant capacity and minimizing mucosal damage.
Keywords Silver Nanoparticles; Butea Monosperma; Anti-Ulcer Activity.
Field Biology > Agriculture / Botany
Published In Volume 6, Issue 1, January-February 2024
Published On 2024-02-02
Cite This Green Synthesis of Silver Nanoparticles from Bark Extract to Detect Anti Ulcer Activity in Swiss Albino Rats - Kalpana p Ghoshal, Ajay Ghatole - IJFMR Volume 6, Issue 1, January-February 2024. DOI 10.36948/ijfmr.2024.v06i01.12392
DOI https://doi.org/10.36948/ijfmr.2024.v06i01.12392
Short DOI https://doi.org/gtgs67

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