International Journal For Multidisciplinary Research

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Postmenopausal bleeding: confrontation between ultrasound data and pathological results

Author(s) Prof. Dr. Nadia nadia Marwen, Dr. Sahla Sahla Zrigue, Dr. Ekram Ekram GUERBEJ, Prof. Dr. Ridha Ridha Fatnassi
Country Tunisia
Abstract Abstract
Introduction: Postmenopausal bleeding (PMB) is a common reason for consultation in gynecology. Endovaginal ultrasound (EVU) represents the first-line paraclinical examination. The objectives of our study were to analyze the sonographic findings in cases of PMB and to assess the correlation between EVU data and histopathological results.
Materials and Methods: We conducted a retrospective, descriptive, and analytical study including patients presenting with PMB, collected in the Department of Gynecology and Obstetrics of Ibn El Jazzar Hospital in Kairouan, over a 10-year period from January 1, 2014, to December 31, 2024.
Results: During the study period, data from 253 patients were collected. The mean age of the patients was 58 years. The mean age at menopause was 49.3 years, and the mean duration of menopause at the onset of bleeding was 8.42 years. EVU was performed in all cases. The sensitivity of EVU in detecting endometrial pathology was 87.52%, with a specificity of 75%, a positive predictive value (PPV) of 89.25%, and a negative predictive value (NPV) of 54%. For an endometrial thickness threshold of 4 mm, the sensitivity of EVU in diagnosing endometrial cancer was 100%, with a specificity of 25.34%, a PPV of 23.48%, and an NPV of 100%.
Conclusion: Given its performance and simplicity, EVU remains the first-line screening examination for the assessment of postmenopausal bleeding.
Keywords Postmenopausal bleeding , Menopause , Endometrial cancer , Endovaginal ultrasound , Histology
Field Medical / Pharmacy
Published In Volume 7, Issue 6, November-December 2025
Published On 2025-11-15
DOI https://doi.org/10.36948/ijfmr.2025.v07i06.60235
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