International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

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Volume 8 Issue 3
May-June 2026

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Pediatric Obesity and Metabolic Syndrome: A Global Epidemic with Emerging Pharmacotherapeutic and Drug Delivery Perspectives

Author(s) Dr. Venugopal Reddy Iragamreddy
Country India
Abstract Pediatric obesity has evolved into a global epidemic with profound implications for public health, particularly due to its strong association with metabolic syndrome and long-term cardiometabolic morbidity. The rising prevalence across both developed and developing countries reflects a complex interplay of genetic susceptibility, environmental influences, and behavioural factors. Metabolic syndrome in children encompasses central obesity, insulin resistance, dyslipidaemia, hypertension, and impaired glucose metabolism, which collectively increase the risk of type 2 diabetes mellitus and cardiovascular disease later in life. This review comprehensively explores the epidemiology, pathophysiological mechanisms, diagnostic frameworks, and clinical sequelae of pediatric obesity and metabolic syndrome. Furthermore, it critically evaluates current and emerging pharmacological interventions, including glucagon-like peptide-1 receptor agonists and insulin sensitizers. A major focus is placed on advances in drug delivery technologies such as nanocarriers, sustained-release systems, and targeted delivery strategies that enhance therapeutic efficacy and adherence in pediatric populations. Addressing pediatric obesity requires an integrated, multidisciplinary approach combining prevention, early diagnosis, lifestyle modification, pharmacotherapy, and innovative delivery systems.
Keywords Pediatric obesity, metabolic syndrome, insulin resistance, GLP-1 receptor agonists, drug delivery systems, childhood obesity, pharmacotherapy
Field Medical / Pharmacy
Published In Volume 8, Issue 3, May-June 2026
Published On 2026-05-11
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E-ISSN 2582-2160
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