International Journal For Multidisciplinary Research

E-ISSN: 2582-2160     Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 8, Issue 4 (July-August 2026) Submit your research before last 3 days of August to publish your research paper in the issue of July-August.

Comprehensive Pharmacognostical Standardization, Bioactive Phytochemical Analysis and Development of a Sterile Phytopharmaceutical Cream from Tridex Procumbensforacceleratedhealingindiabetic Foot Ulcers

Author(s) Prof. Ezhilarasi D, Madhavan, Maniyarasan, Madhumitha M, Ranjini N, Mariyalilly princy KV
Country India
Abstract Diabetic foot ulcers (DFUs) represent a major healthcare challenge affecting approximately 12-25% of diabetic patients worldwide. This study aimed to develop and evaluate a sterile topical herbal cream incorporating Tridax procumbens leaf extract for wound healing in diabetic foot ulcers. Fresh leaves of Tridax procumbens were collected, authenticated, and subjected to pharmacognostical and phytochemical evaluation. Soxhlet extraction using ethanol was performed to obtain the crude extract. The extract wasformulated into a water-in-oil (W/O) sterile cream under aseptic conditions. Pharmacognostical analysis confirmed the authenticity of the plant material through macroscopic and microscopic characterization. Phytochemical screening revealed the presence of flavonoids, tannins, alkaloids, saponins, phenolic compounds, and glycosides. The formulated creamexhibitedacceptablephysicochemicalparametersincludingpH5.62-7.1,goodspreadability(28.84-34.09 g•cm/sec), and excellent washability. Stability studies demonstrated no significant changes in color, odor, texture, or phase separation over 30 days. The results validate the traditional use of Tridax procumbens in wound management and support the development of this formulation as a cost-effective, safe, and biologically active alternative for diabetic foot ulcer treatment.
Field Medical / Pharmacy
Published In Volume 8, Issue 4, July-August 2026
Published On 2026-08-07

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